Department of Pathology

Director:

  • Prof. Dr. med. Christoph Röcken


The Department of Pathology is a nationally and internationally renowned department, whose Section for Haematopathology is part of the Kiel Lymphknotenregister (Lymph Node Registry), and whose Section for Paediatric Pathology is part of the Kiel Kindertumorregister (Paediatric Tumour Registry) and the Amyloid Register Kiel.

The main research areas are in the pathology and pathogenesis of malignant tumours in adults and children. The research is aimed at improving the early detection of malignant tumours using non-invasive methods and to be able to predict more accurately the biological behaviour (prognosis) and responses to treatment (prediction, individualised treatment) of malignant tumours.

The Department covers the entire spectrum of modern university pathologies in health care. This includes histopathology, cytopathology, immunopathology, molecular pathology and obductions pathology. It is involved in complete cell and tissue based diagnostics of human disease and of course the use of molecular diagnostics for the adjustment of target-oriented treatments.

The Amyloid Register Kiel is dedicated to conformational illnesses. It collects and documents cases with amyloidoses for research purposes, to develop new diagnostic and classification methods and to improve the treatment of amyloidoses.

Section for Haematopathology

Head of the Section:

  • Prof. Dr. Wolfram Klapper


The Section for Haematopathology and Lymph node registry is the birthplace of the "Kiel classification", created by Professor Karl Lennert, which was the first modern classification of malignant lymphomas. Diseases of the blood, bone marrow and the lymphatic tissues are diagnosed and researched in this Section, using the latest histopathological and molecular pathological methods.

The Section is a reference centre for all lymphoma studies for German researchers, nominated by the Competence Network Malignant Lymphomas and the leading reference pathology for paediatric non-Hodgkin's lymphoma (NHL- BFM), the Europäische Mantelzelllymphom Netzwerk (European mantle cell lymphoma network) and the German Hodgkin Study Group for low grade non-Hodgkin's lymphoma (GLSG).
 

Section for Paediatric Pathology

Head of the Section:

  • N.N.

 
The Section for Paediatric Pathology is the home of the Paediatric Tumour Registry of the German Society of Paediatric Oncology and Haematology (GPOH). This national reference centre was set up in 1977 and since then has reviewed around 50,000 tumour samples and examined them scientifically.

Each year, approx. 1,800 solid paediatric and young patient tumours are examined. These patients are primarily being treated as part of treatment optimisation studies run by the GPOH, but increasingly they originate from other European countries and from all over the world. On top of this, an increasing number of soft tissue sarcomas from adult patients are also examined. The tumour samples are classified and stage adjusted according to valid classifications and are also additionally investigated as part of biological follow-up programmes of treatment optimisation studies. The focus here is on soft tissue sarcomas, in particular rhabdomyosarcomas, nephroblastomas, malignant liver tumours and germ cell tumours, which are all analysed to determine their molecular genetic heterogeneity and the expression of treatment relevant proteins. The paediatric tumour registry receives financial support from the Deutsche Krebshilfe (German Cancer Aid).