Institute of Experimental Cancer Research - Section for Molecular Oncology

Director:

  • Prof. Dr. Susanne Sebens


The Institute of Experimental Cancer Research (IET) was established in 2009 as part of the Krebszentrum Nord/Comprehensive Cancer Center within the framework of the application for an oncological centre of excellence. The Section for Molecular Oncology has been part of the IET since then. 

The Section began in the 1990s, as part of a research group located in the Department of General and Thoracic Surgery at the Kiel Campus of the UKSH. In 2004, the Section for Molecular Oncology was founded as a separate structural institution with the support of a Foundation Professorship of Deutsche Krebshilfe (German Cancer Aid).

The oncological Biobank BMB CCC is operated jointly with the Department of General Surgery, Abdominal, Thoracic, Transplantation and Paediatric Surgery and the Department of Pathology and is a member of the central biobank network (P2N) of the Faculty of Medicine. The P2N network is supported as part of the biobank initiative by the Federal Ministry of Education and Research.

Research is currently conducted in the causes of the formation, apoptosis resistance mechanisms and progression of gastrointestinal tumours. Oncogenic factors that we have recently discovered, known as death receptors, play a major role in this. The molecular biological diagnostics of the metastasis of these tumours is another research focus. Biomarkers are also useful here, to evaluate whether adjuvant treatment modes are indicated and their chances of success, and to set up corresponding, optimised, pre-clinical in vitro and in vivo model systems. This also occurs in close cooperation with the imaging centre MOIN-CC and the Cluster of Excellence 'Inflammation at Interfaces'.