National and International Group Projects

DFG Group Projects
 

Priority Programmes

SPP 1580: Intracellular compartments as places of pathogenhost-interactions
Sub-project: Lysosomal Membrane Proteins and their Roles in Phagosome Maturation
Prof. Paul Saftig, Institute of Biochemistry
Funding time frame: August 2014 - July 2020

SPP 1710: Dynamics of thiol-based redox switches in cellular physiology
Sub-project: Protein-disulfide isomerase: the decisive off-switch of a disintegrin and metalloprotease-17
Dr. Inken Lorenzen, Institute of Biochemistry
Funding time frame: April 2014 - March 2017

Research Units

FOR 5042: miTarget: The micriobiome as a therapeutic target in inflammatory bowel diseases
Prof. André Franke, Institute of Clinical Molecular Biology
Funding time frame: 2020-  2023

FOR 2969: Mechanisms of antibody light chain misfolding in systemic AL amyloidosis
Sub-project: Analysis of the pathological effects of light chains and AL protein states
Prof. Christoph Röcken, Department of Pathology
Funding time frame: 2019 - 2022

FOR 2799: Receiving and Translating Signals via the gamma-delta T Cell Receptor
Sub-project: Einfluss bispezifischer Antikörper auf die Interaktion von yo T-Zellen und Tumorzellen
Prof. Daniela Wesch, Department of Immunology
Funding time frame: 2018 - 2021

FOR 2715: Epileptogenesis of genetic epilepsies 
Sub-project: Genetische Mechanismen epileptischer Enzephalopathien
Prof. Ingo Helbig, Department of Pediatric and Adolescent Medicine II
Funding time frame: 2017- 2020

FOR 2143: Interneuron Synpatic Plasticity
Sub-project: Functional relevance of interneuron plasticity in the dentate gyrus 
Prof. Peer Wulff, Institute of Phsyiology (Speaker)
Funding time frame: January 2015 - December 2020

FOR 2093: Memristive Devices for Neural Systems 
Sub-project: Translational modelling of memristive learning
Prof. Thorsten Bartsch, Department of Neurology
Funding time frame: 2014 - 2020

FOR 2107: Neurobiologie affektiver Störungen - Eine translationale Perspektive auf Gehirnstruktur und -funktion
Sub-project: Multimodal Cross-Disorder Biotype Identification and Multimethod Data Analytic Support
Prof. Astrid Dempfle, Department of Medical Informatics and Statistics
Funding time frame: 2014 - 2020

FOR 2625: Mechanisms of Lysosomal Homeostasis
Sub-project: Deciphering the physiological roles of the lysosomal phosphatidylinositol- 4,5-bisphosphate 4-phosphatases TMEM55A and TMEM55B
Prof. Paul Saftig, PD Dr. Markus Damme, Institute of Biochemistry
Funding time frame: August 2017 - July 2020

FOR 2518: Funktionale Dynamik von Ionenkanälen und Transportern - DynIon
Sub-project: The role of selectivity filter ion occupancy in voltage gating and inactivation gating in potassium channels
Prof. Thomas Baukrowitz, Institute of Phsyiology
Funding time frame: January 2017 - December 2019

 

BMBF Group Projects
 

The National Cohort (NaKo)
Prof. Wolfgang Lieb, Institute of Epidemiology
Funding time frame: May 2013 - April 2023

GUIDE-IBD – Molekulare Therapiesteuerung bei Chronisch-entzündlichen Darmerkrankungen
Prof. Stefan Schreiber, Institut für Klinische Molekularbiologie
Förderung: Juni 2019 – Mai 2022

CONNECT-GENERATE
Prof. Frank Leypoldt, Institut für Klinische Chemie, Department of Neurology
Sub-project: IMPROVE-GENERATE
Prof. Frank Leypoldt, Institut für Klinische Chemie, Department of Neurology
Sub-project: Aufklärung der genetischen Prädisposition bei Autoimmunenzephalitis
Prof. Gregor Kuhlenbäumer, Klinik für Neurologie
Prof. Frank Leypoldt, IInstitute of Clinical Chemistry, Department of Neurology
Sub-project: Anwendung fortschrittlicher Längsstruktur-MRT-Analysen bei Autoimmunenzephalitis
Prof. Thorsten Bartsch, Department of Neurology
Funding time frame: May 2019 - April 2022

TRANSCAN V - NOVEL: early diagnosis, diagnosis of disease progression and progression prediction of lymph node cancer
Prof. Claudia Baldus, Medical Department II specialised in hematology and oncology
Funding time frame: May 2019 - April 2022

MIGBAN - Interaktion zwischen Darm-Mikrobiom und Gehirn bei Anorexia Nervosa
Sub-project: Mikrobiomanalysen  
Prof. John Baines, Institute for Experimental Medicine
Funding time frame: April 2019 - March2022

Frühdetektion von Schmerzchronifizierung (NoChro)
Teilvorhaben: Entwicklung eines sensorischen Messprotokolls mit Modalitäten-spezifischen evozierten Potenzialen

PD Dr. Philipp Hüllemann, Department of Neurology
Funding time frame: February 2019 - January 2022

Children’s Automated Intelligent REsuscitation – Intelligente automatisierte Wiederbelebung von Kindern (CLAIRE) –
Teilvorhaben: Erforschung der Kinderreanimation und Usabilityuntersuchung eines mechanischen Thoraxkompressionssystems für Kinder

Prof. Thorsten Gräsner, Institut für Rettungs- und Notfallmedizin
Funding time frame: January 2019 – December 2021
Teilvorhaben: Realistische Simulation pädiatrischer Reanimationen am Großtiermodell
Prof. Matthias Grünewald, Department of Anaesthesiology and Intensive Care Medicine
Funding time frame: January 2019 – December 2021

AgeWell.de – Eine multizentrische cluster-randomisierte kontrollierte Multikomponenten-Interventionsstudie zur Prävention kognitiver Abbauprozesse bei älteren Hausarztpatienten
Prof. Hanna Kaduszkiewicz, Department of General Medical Practice
Funding time frame: August 2017 - July 2021

e.Med Nachwuchsgruppe ComorbSysMed – Untersuchung von Komorbiditäten in ent-zündlichen Hauterkrankungen mittels Methoden des Maschinellen Lernens und Omics-Technologie
Dr. Silke Szymczak, Department of Medical Informatics and Statistics
Funding time frame: July 2016 – June 2021

Echtzeit-Registrierung und Tracking bei der schonenden retinalen Lasertherapie( Re-giLas)- Teilvorhaben: Vorklinische und klinische Erprobung
Prof. Johann Roider, Department of Opthalmology
Funding time frame: March 2018 – February 2021

HIGHmed: Medizininformatik – Konsortium, Beitrag UKSH, Institut für Medizinische Informatik und Statistik
Prof. Björn Bergh, Department of Medical Informatics and Statistics
Funding time frame: September 2018 - December 2019

GB-XMAP - Entwicklung einer systemtheoretischen Methodik zur Charakterisierung einer veränderten Genexpression bei psychischen Krankheiten und chronisch-entzündlichen Darmerkrankungen, Anteil Kiel
Prof. David Ellinghaus, Institute of Clinical Molecular Biology
Funding time frame: November 2017 – October 2019

coNfirm – Netzwerke der Herzerkrankungen, Systemmedizinischer Ansatz zur Verbesserung der Herzgesundheit – Bioinformatische Ansätze zur Generierung von ge-meinsamen Signalwegen kardialer Erkrankungen (TP2)
Dr. Silke Szymczak, Department of Medical Informatics and Statistics
Funding time frame: November 2017 – October 2019

Zwanzig20 – InfectControl 2020 - Verbundvorhaben: Antigen-reaktive T-Zellen zur Di-agnose und Therapie von Schimmelpilz-assoziierten Erkrankungen in Risikopatienten; TP7: ART4Fun – TV7
Prof. Alexander Scheffold, Department of Immunology
Funding time frame: January 2019 – August 2019

Mg Bone - Multimodale Bildgebung zur strukturellen Analyse der Knochenmodellie-rung induziert durch abbaubare Magnesiumimplantate, Teilprojekt 1
Prof. Claus Glüer, Department of Radiology and Neuroradiology
Funding time frame: July 2016 – June 2019

BioAsset: Individualisierte Beurteilung und Behandlung von Osteoporose auf biome-chanischer Grundlage; Mikrostruktur( TP4), Materialeigenschaften( TP5) und Diagnostik (TP6)
Prof. Claus Glüer, Department of Radiology and Neuroradiology
Funding time frame: July 2010 - June 2019

SYMBOL-HF (Junior research alliances in systems medicine)
Prof. Derk Frank, Medical Department III, cardiology
Funding time frame: April 2015 - March 2019

UDEMM - Umweltmonitoring für die Delaboration von Munition im Meer: Vorhaben: Entwicklung eines Ökologisch-Toxikologischen Biomonitorings für Schadstoff-Emissionen aus Munition im Meer
Funding time frame: March 2016 – February 2019

EPItect - Pflegerische Unterstützung epilepsiekranker Menschen durch innovative Ohrsensorik
Prof. Ulrich Stephani, Department of Pediatric and Adolescent Medicine
Funding time frame: March 2016 - February 2019

SysInflame - A Systems Approach to Chronic Inflammatory Disease
Prof. Stefan Schreiber/Prof. Philip Rosenstiel, Institute of Clinical Molecular Biology
Funding time frame: February 2017 - January 2019

Netzwork for neuronal Ceriod-neuronal lipofuscinosis (NCL2TREAT)
Sub-project: Development of a therapeutic correction of the autophagocytic flux in an NCL model via preclinical an enzyme replacement therapy with recombinant Cathepsin-D 
Prof. Paul Saftig, Institute of Biochemistry
Funding time frame: February 2016 - January 2019

RETOME - Monitoring von Retinatherapien @ home - Teilvorhaben: Klinische Entwick-lung und Evaluierung eines Gerätes und eines Algorithmus zum heimbasierten Monitoring von IVOM-Therapien bei altersbedingter Makuladegeneration, diabetischer Makulopathie und ver-schlussbedingtem Makulaödem
Prof. Johann Roider, Department of Opthalmology
Funding time frame: July 2015 – January 2019

LiSyM - Liver Systems Medicine: Pillar I - Metabolischer Frühschaden (EMI), TP6
Prof. Clemens Schafmeyer, Department of General Surgery and Thoracic Surgery
Funding time frame: January 2016 – December 2018

e.Med: Modul II, MMML-Demonstators - Molekulare Mechanismen in Malignen Lym-phomen - Teilprojekt D
Prof. Wolfram Klapper, Department of Hematopathology
Funding time frame: March 2015 - December 2018

Ethical, social and regulatory aspects of citizen science in the healthcare sector
Prof. Alena Buyx, Institute of Experimental Medicine
Funding time frame: April 2014 - December 2018

Imprintingerkrankungen - klinisches Spektrum und pathogenetische Mechanismen (Imprinting), Teilprojekt 5
Prof. Ammerpohl, Department of Human Genetics, with PD Dr. Müller, ZIP
Funding time frame: June 2015 – May 2018

VarWatch - Pilotierung einer transienten Datenbank für genetische Varianten ungeklär-ter klinischer Signifikanz
Prof. Michael Krawczak, Department of Medical Informatics and Statistics
Funding time frame: June 2015 – May 2018

Deutsches Epigenom Projekt (DEEP - German Epigenome Project), part of the International Human Epigenome Consortium (IHEC)
Prof. Philip Rosenstiel, Institute of Clinical Molecular Biology
Funding time frame: September 2012 - December 2017

InTraSig: Development of a personalized anti-inflammatory treatment for inhibition of interleukin-6 signalling
Prof. Stefan Rose-John, Institute of Biochemistry
Funding time frame: September 2014 - August 2017

Innovative Imaging & Intervention in early AMD (I-cube)
Prof. Johann Roider, Department of Ophthalmology
Funding time frame: March 2013 - February 2017

 

BMWi
 

EnOB: ULTRA-F: Ultrafiltration als Element der Energieeffizienz in der Trinkwas-serhygiene – Teilvorhaben: Felduntersuchungen auf Basi der DVGW-Rahmenbedingungen mit wissenschaftlicher Vertiefung
Prof. Helmut Fickenscher, Department of Infection Medicine
Funding time frame: November 2018 - October 2022

 

G-BA
 

MundZaRR – Mundgesundheitsverbesserung durch zahnärztlich delegierte, pflegebegleitende Remotivation und Reinstruktion
Prof. Katrin Hertrampf, Department of Oral and Maxillofacial Surgery
Funding time frame: June 2019 – May 2022

Making SDM A REALITY – Vollimplementierung von Shared Decision Making im Krankenhaus
Prof. Martin Schrappe, Department of Pediatric and Adolescent Medicine I
Funding time frame: October 2017 – September 2021

 

Krebshilfe

OLIGOMA - Randomisierte, multizentri-sche Prüfung der Wirksamkeit und Sicherheit einer lokalen Strahlentherapie von Metastasen als Ergänzung zur Standardtherapie bei Patientinnen mit oligometastasiertem Mammakarzinom
Prof. Jürgen Dunst, Department of Radiotherapy
Funding time frame: April 2019 - September 2024

Multizentrische Therapiestudie zur Behandlung von Kindern und Jugendlichen mit akuter Lympho-blastischer Leukämie
Prof. Martin Schrappe, Prof. Gunnar Cario, Department of Pediatric and Adolescent Medicine I
Funding time frame: February 2019 - January 2027

Prospektive, multizentrische, vergleichende Studie des Rekurrenz-freien Überlebens nach Lebertransplantation in zwei Tumorstadium-definierten Gruppen (Milan-in versus Milan-out/UCSF-in) von Patienten mit hepatozellulärem Karzinom (HCC) in Zirrho-se und loko-regionärer Therapie zur Überbrückung der Wartezeit
Prof. Felix Braun, Department of General Surgery and Thoracic Surgery
Funding time frame: January 2019 – December 2025

Verbesserung der CD38-Antikörpertherapie bei der akuten lymphoblastischen Leukämie im Kindesalter durch Fc-Engineering
PD Dr. Denis Schewe, Department of Pediatric and Adolescent Medicine I
Funding time frame: 2019 - 2022

Einfluss der hepatischen Mikroumgebung auf die Ausbildung von Lebermetastasen beim duktalen Pankreasadenokarzinom
Prof. Susanne Sebens, Institute of Experimental Cancer Research
Funding time frame: January 2018 - October 2022

Die Bedeutung von circRNAs und fusion-circRNAs in der akuten lymphoblastischen Leukämie
Prof. Claudia Baldus, Medical Department II specialised in hematology and oncology
Funding time frame: January 2019 - December 2021

Akute Lymphoblastische Leukämie im Rezidiv: Entschlüsselung der molekularen Me-chanismen zur Überwindung der Therapieresistenz
Prof. Claudia Baldus, Medical Department II specialised in hematology and oncology
Funding time frame: January 2019 - December 2020

Umfassendes Verständnis der Immuncheckpointinhibition bei Patienten mit Hodgkin Lymphom in frühen Stadien: Therapiebegleitende translationale Analysen
Prof. Wolfram Klapper, Department of Pathology, Section for Haematopathology
Funding time frame: July 2017 – June 2019

 

EU Projects
 

3TR - Identification of the Molecular Mechanisms of non-response to Treatments, Re-lapses and Remission in Autoimmune, Inflammatory, and Allergic Conditions
Prof. Philip Rosenstiel, Institute of Clinical Molecular Biology  
Funding time frame: September 2019 – September 2026

BIOMAP - Biomarkers in Atopic Dermatitis and Psoriasis
Prof. Stephan Weidinger, Department of Dermatology and Allergology
Funding time frame: April 2019 – March 2024

MOBILISE-D - Connecting digital mobility assessment to clinical outcomes for regula-tory and clinical endorsement
Prof. Walter Maetzler, Department of Neurology
Funding time frame: April 2019 – March 2024

EASI-GENOMICS - European Advanced infraStructure for Innovative Genomics
Prof. Andre Franke, Institute of Clinical Molecular Biology
Funding time frame: February 2019 – January 2024

CARDIOREGENIX - Development of Next-Generation Gene Therapies for Cardiovas-cular Disease
Prof. Oliver Müller, Medical Department III specialised in cardiology and angiology
Funding time frame: January 2019 – December 2023

pHioniC - pH and Ion Transport in Pancreatic Cancer
Prof. Anna Trauzold, Institute of Experimental Medicine
Funding time frame: November 2018 - October 2022

WELMO - Wearable Electronics for Effective Lung Monitoring
Prof. Inéz Frerichs, Department of Anaesthesiology and Intensive Care Medicine
Funding time frame: January 2019 – June 2022

IMI PainCare- Improving the care of patients suffering from acute or chronic pain
Prof. Ralf Baron, Department of Neurology
Funding time frame: April 2018 - March 2022

SYSCID - A Systems medicine approach to chronic inflammatory disease
Prof. Philip Rosenstiel, Institute of Clinical Molecular Biology
Funding time frame: January 2017 - March 2022

EU-STANDS4PM - A European standardization framework for data integration and data-driven in silico models for personalized medicine
Prof. Philip Rosenstiel, Institute of Clinical Molecular Biology
Funding time frame: January 2019 – December 2021

STIPED - Transcranial brain stimulation as innovative therapy for chronic pediatric neuropsychiatric disorders
Dr. Uwe Niederberger, Department of Medical Psychology and Medical Sociology
Prof. Alena Buyx, Institute ofExperimental Medicine, Section for Medical Ethics
Prof. Astrid Dempfle, Department of Medical Informatics and Statistics
Funding time frame: January 2017 - December 2021

GIF - Inhibiting malignant EGF-R activity by targeting ADAM17 (TACE) as a novel al-ternative therapeutic strategy
Prof. Stefan Rose-John, Institute of Biochemistry
Funding time frame: October 2018 – September 2021

KEEP CONTROL - Industrial Academic Initial Training Network towards specific diagnosis and treatment of age-related gait and balance deficit
Prof. Walter Maetzler, Department of Neurology
Funding time frame: March 2017 - February 2021

MJFF - Structural characterization of the GCase/LIMP-2 complex – a translational approach
Dr. Friederike Zunke, Institute of Biochemistry
Funding time frame: November 2018 – November 2019

DANONE - Modulation of enteric and central gliosis by casein derivedbioactive peptides
Dr. François Cossais, Institute of Anatomy
Funding time frame: January 2018 – July 2019

ChiLTERN - Children´s Liver Tumour European Research
Prof. Ivo Leuschner, Department of Pathology
Funding time frame: January 2016 - December 2020

FAIR-PARK-II - Conservative iron chelation as a disease-modifying strategy in Parkinson's disease: a multicentric, parallel group, placebo-controlled, randomized clinical trial of deferiprone
Prof. Daniela Berg, Prof. Walter Maetzler, Department of Neurology
Funding time frame: April 2016 - April 2020

DOLORisk - Understanding risk factors and determinants for neuropathic pain
Prof. Ralf Baron, Department of Neurology
Funding time frame: July 2015 - March 2020

CRADL - Continuous Regional Analysis Device for neonatal Lung
Prof. Inés Frerichs, Department of Anaesthesiology and Surgical Intensive Care
Funding time frame: September 2015 - August 2019

NIH - Biochemical and biophysical nature of Claudin-16 and Claudin-19-Channels
Prof. Markus Bleich, Institute of Physiology
Funding time frame: May 2015 - April 2019

DESIRE - Development and Epilepsy - Strategies for Innovative Research to improve diagnosis, prevention and treatment in children with difficult to treat Epilepsy
Prof. Ulrich Stephani, Department of Neuropaediatrics
Funding time frame: October 2013 - September 2018

InnoCan - Innovative High Technology Cancer Treatment, Denmark-Germany
Prof. Jürgen Dunst, Department of Radiotherapy
Funding time frame: July 2015 - June 2018

PROMETHEUS - PROject for a Medically Educated, Transformed, HEalthy, and United Society
Prof. Klaus-Peter Jünemann, Department of Urology
Funding time frame: July 2015 - June 2018

EUROCLAST - Exploring Functional and Developmental Osteoclast Heterogeneity in Health and Disease
Prof. Paul Saftig, Institute of Biochemistry
Funding time frame: September 2013 - June 2018

SysmedIBD - Systems medicine of chronic Inflammatory Bowel Disease
Prof. Philip Rosenstiel, Institute of Clinical Molecular Biology
Funding time frame: December 2012 - November 2017

WELCOME - Wearable Sensing and Smart Cloud Computing for Integrated Care to COPD Patients with Co-morbidities
Prof. Inéz Frerichs, Department of Anaesthesiology and Surgical Intensive Care
Funding time frame: November 2013 - October 2017

ExPO-r-NeT - European Expert Paediatric Onkology Reference Network for Diagnostics and Treatment
Prof. Martin Schrappe, Department for General Paediatrics
Funding time frame: March 2014 - August 2017

 

Interreg A/B
 

North Sea Wrecks
Prof. Edmund Maser, Department of Toxicology
Funding time frame: July 2018 – October 2022

CCC- Changing Cancer Care
Prof. André Franke, Institute of Clinical Molecular Biology
Funding time frame: January 2019 – December 2021

HERACLES
Prof. Klaus-Peter Jünemann, Department of Urology and Paediatric Urology
Funding time frame: September 2018 – August 2021

FucoSan
Prof. Alexa Klettner, Department of Opthalmology
Funding time frame: April 2017 - March 2020

BALTIC BLUE Biotechnology Alliance
Prof. Alexa Klettner, Department of Opthalmology
Funding time frame: March 2017 - February 2019